Director's Message

The mission of the University of Missouri Laboratory for Infectious Disease Research is to provide state of the art facilities to support research on infectious diseases. Our goal is to foster research in the development of novel approaches to prevent and treat diseases caused by some of our most deadly pathogens.






  • LIDR Fosters Research for the Advancement of Vaccines and Therapeutics
  • LIDR BSO, Dr. Travis McCarthy, Elected to MABioN Executive Council
  • MRIGlobal and University of Missouri earn Zika study grant
  • Recent LIDR Publications

  • Ludlow A.B., Pauling C.D., Marketon M.M., Anderson D.M. (2019) Drosophila as a Model for Understanding the Insect Host of Yersinia pestis. In: Vadyvaloo V., Lawrenz M. (eds) Pathogenic Yersinia. Methods in Molecular Biology, vol 2010. Humana, New York, NY
  • Anderson P.E., Olson R.M., Willix J.L., Anderson D.M. (2019) Standardized Method for Aerosol Challenge of Rodents with Yersinia pestis for Modeling Primary Pneumonic Plague. In: Vadyvaloo V., Lawrenz M. (eds) Pathogenic Yersinia. Methods in Molecular Biology, vol 2010. Humana, New York, NY
  • Olson RM, Anderson DM. 2019. Shift from primary pneumonic to secondary septicemic plague by decreasing the volume of intranasal challenge with Yersinia pestis in the murine model. PLoS One.
  • Lacey, et al. 2018. Caspase -1 and Caspase -11 Mediate Pyroptosis, Inflammation, and Control of Brucella Joint Infection. Infect Immun.
  • Lacey, et al. 2019. IFN‐γ‐dependent nitric oxide suppresses Brucella‐induced arthritis by inhibition of inflammasome activation. J Leukoc Biol.
  • Kantor, et al. 2019. Infection Pattern of Mayaro Virus in Aedes aegypti (Diptera: Culicidae) and Transmission Potential of the Virus in Mixed Infections With Chikungunya Virus. J Med Entomol.
  • Olson, et al. 2019. Yersinia pestis exploit early activation of myeloid differentiation primary response 88 (MyD88) for growth in the lungs during pneumonic plague. Infect Immun.
  • Cherla et al. 2018Coxiella burnetii Inhibits Neutrophil Apoptosis by Exploiting Survival Pathways and Antiapoptotic Protein Mcl-1. Infect Immun.
  • Kantor et al. 2018. Ultrastructural Analysis of Chikungunya Virus Dissemination from the Midgut of the Yellow Fever Mosquito, Aedes aegypti. Viruses.
  • Sheridan et al. 2018. African and Asian strains of Zika virus differ in their ability to infect and lyse primitive human placental trophoblast. PLoS One.
  • Xia et al. 2018. Viral dedication to vigorous destruction of interferon receptors. Virology.
  • Buttrum et al. 2018. Both major histocompatibility complex class I (MHC-I) and MHC-II molecules are required, while MHC-I appears to play a critical role in host defense against primary Coxiella burnetii infection. Infect Immun.
  • Whyte et al. 2018. Inactivation of porcine interleukin-1beta results in failure of rapid conceptus elongation. Proc Natl Acad Sci U S A.
  • Skyberg and Lacey 2017. Hematopoietic MyD88 and IL-18 are essential for IFN-gamma-dependent restriction of type A Francisella tularensis infection. J Leukoc Biol.
  • Dhariwala et al. 2017. Induction of type I interferon through a noncanonical toll-like receptor 7 pathway during Yersinia pestis infection. Infect Immun.
  • Olson and Anderson 2017. Usurping bacterial virulence factors as self-delivery vehicles for therapeutic use. Virulence.
  • Dong et al. 2017. Chikungunya virus dissemination from the midgut of Aedes aegypti is associated with temporal basal lamina degradation during bloodmeal digestion. PLoS Negl Trop Dis.
  • Dong et al. 2017. The midgut transcriptome of Aedes aegypti fed with saline or protein meals containing chikungunya virus reveals genes potentially involved in viral midgut escape. BMC Genomics.
  • Lacey et al. 2017. Temporal role for MyD88 in a model of brucella-induced arthritis and musculoskeletal inflammation. Infect Immun.
  • Sheridan et al. 2017. Vulnerability of primitive human placental trophoblast to Zika virus. Proc Natl Acad Sci U S A.
  • Kantor et al. 2017. Identification and initial characterization of matrix metalloproteinases in the yellow fever mosquito, Aedes aegypti. Insect Mol Biol.
  • Olson and Anderson 2017. Fractionation techniques to examine effector translocation. Meth Mol Biol.
  • Previous LIDR Publications - 2011 through 2016

    Aerobiology Core

    Immunology Core

    Microbiology Core